Protein Variants DB

This site is dedicated to the Protein Variants project, a joint initiative of the Laboratory of Bioinformatics and Computational Biology of the Institute of Food Science, National Research Council, and the Department of Chemistry and Biology "A.Zambelli", University of Salerno, Italy.

Three databases have been developed and are available at this site:

- Galactosemia Protein Database (Refs. 1-3)

- Menin protein database (Ref. 4)

- Eotaxin-3 Mutation Database (Ref. 5)

References to the databases:
  1. d'Acierno A, Facchiano A, Marabotti A. (2009)
    GALT Protein Database, a bioinformatics resource for the management and analysis of structural features of a galactosemia-related protein and its mutants.
    Genomics Proteomics Bioinformatics 2009, 7, 71-76. doi: 10.1016/S1672-0229(08)60035-2. PMID: 19591794

  2. d'Acierno A, Facchiano A, Marabotti A. (2014)
    GALT Protein Database: querying structural and functional features of GALT enzyme.
    Hum Mutat. 2014 35, 1060-1067. doi: 10.1002/humu.22613. PMID: 24990533

  3. d'Acierno A, Scafuri B, Facchiano A, Marabotti A. (2018)
    The evolution of a Web resource: The Galactosemia Proteins Database 2.0.
    Hum Mutat. 2018 Jan;39(1):52-60. doi: 10.1002/humu.23346. PMID: 28961353

  4. Biancaniello C, D'Argenio A, Giordano D, Dotolo S, Scafuri B, Marabotti A, d'Acierno A, Tagliaferri R, Facchiano A. (2022)
    Investigating the Effects of Amino Acid Variations in Human Menin.
    Molecules, 27, 1747. doi: 10.3390/molecules27051747. PMID: 35268848.

  5. Giordano D, d'Acierno A, Marabotti A, Iovino P, Iacomino G, Facchiano A. (2024)
    Bioinformatics Study on Site-Specific Variations of Eotaxin-3, a Key Chemokine in Eosinophilic Esophagitis (EoE)
    Genes (Basel). 2024 Aug 14;15(8):1073. doi: 10.3390/genes15081073. PMID: 39202432